Scott Klasky
Research Scientist
Oak Ridge National Lab, University of Tennessee

From Innovation to Impact: Research and Development in Data Intensive High Performance Computing

Sept 14th, 2011

As we move closer to extreme scale computing, applications face numerous challenges that must be addressed before they can deliver breakthrough science. I/O is one of the major challenges many of the applications are facing at the extreme scale. My team has led the efforts into creating a new paradigm for data management on HPC platforms, which utilizes a Service Oriented Architecture ...

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Ioan Raicu
Assistant Professor
Institute of Technology University

Making a Case for Distributed File Systems at Exascales

April 27th, 2011

Exascale computers will enable the unraveling of significant scientific mysteries. Predictions are that 2019 will be the year of exascales, with millions of compute nodes and billions of threads of execution. The current state-of-the-art storage (but decades-old approach) in High-End Computing (HEC), in which storage is segregated from compute nodes and connected by a network, will not scale with the expected exponential growth in concurrency.

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Danni Yu
Ph.D Student
Purdue University

Noise Reduction in High-throughput Gene Perturbation Screens

August 20th, 2010

Perturbation screens are key for understanding the function of complex organisms. When conducted on genome-wide scale, they provide invaluable global insight into the function of individual gene and gene products, and into their physical and genetic interactions. Recent technological advances enable perturbation screens that are increasingly high in throughput. As a result, the screens now play an important role in functional genomics.

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